Tudca vs. Milk Thistle: What you Need to Know 

Tudca and milk thistle are used to treat liver conditions. 

Some people choose to take both products, but choosing one is the best one to go. But how do you decide between tudca vs. milk thistle?

For starters, it depends on availability. You may not be able to get one product in your region – if this is the case, then go with what you can get. But if you’re spoilt for choice, you’ll have to make a decision.

Tudca is often seen as the better option, so if you can, we’d recommend tudca over milk thistle. (But more on this shortly.)

So, this blog post will discuss tudca vs. milk thistle, providing you with a rundown of both products; the benefits, side effects, and more. 

What is tudca?

Tudca is a metabolite – a secondary product of the bile salt secreted from the liver. 

This water-soluble bile salt is found naturally in the body and is also made in the liver. 

Often, tudca is used to treat a condition called “cholestasis,” also known as liver disease. But it’s also used to help detox the liver – a form of traditional Chinese medicine that has been around for years.

What are the benefits?

  • It’s produced naturally by the body
  • May improve gut health & the gut microbiome 
  • Supports brain function and eye health
  • Improved liver bile flow

These are just a few of the many benefits, but tudca is widely recognized as a beneficial supplement for those with liver disease and other related health conditions. 

Are there any side effects? 

Research on tudca is limited, but side effects may include:

  • Skin issues
  • Sweating
  • Hair thinning
  • Headaches and fatigue 
  • Mental health disturbances (increased depression, anxiety, and sleep disorders)

Other side effects exist, too. But as always, some people may experience a mix of side effects, while others may not encounter any. 

What is milk thistle? 

Milk thistle is a herb found in predominantly Mediterranean countries. 

Similar to tudca, milk thistle is used to treat liver and also gallbladder issues.


One of the main ingredients of the milk thistle herb is “silymarin” – it contains antioxidant compounds that may help treat various conditions by reducing inflammation. 

Related: TUDCA vs. NAC: what’s the difference? 

What are the benefits? 

Benefits of milk thistle may include:

  • Protective effect on liver health
  • Lower cholesterol levels
  • Improved heart health

Despite these potential benefits, research is still lacking on milk thistle. So, take these with a grain of salt.

Are there any side effects? 

When taken for long periods, people may experience side effects, such as:

  • Nausea
  • Stomach issues
  • Itching
  • Bloating


Typically, the side effects are seen to be less adverse than tudca. But once again, side effects vary from person to person.

Note: we’re not medical experts; seek the advice of a doctor before taking tudca or milk thistle. 

Milk thistle vs. tudca: what’s the difference? 

Both tudca and milk thistle supposedly improve and support liver health and function.

Tudca is found naturally in the body in small quantities, whereas milk thistle is obtained from a herb.

Usually, tudca is seen as the better supplement for liver health. However, both tudca vs. milk thistle have their benefits. 

Despite this, the side effects of milk thistle are less common and also seen as less severe. 

Can you take tudca with milk thistle? 

We’d suggest taking either tudca of milk thistle – not both.

Typically, tudca is seen as the safer and more effective option when it comes to liver health and support. 

If you can’t decide between the two, we’d suggest consulting a medical professional – they may have further advice that will support your decision, too. 

FAQs

Can tudca cause liver damage?

Tudca is thought to help the liver, not damage the vital organ. 

Can tudca heal the liver?

The liver plays many roles in the body – detoxifying the liver is thought to improve health, reducing fever, spasms, and even vision problems. Tudca is a supplement that may help support and heal the liver – used as a popular Chinese medical practice for years.

Why should you not take milk thistle? 

Milk thistle may cause an allergic reason in some people, especially if you’re allergic to other herbs and plants in the Asteraceae family. Always contact a medical professional before trying new herbs or supplements.